Polysorbates

Abstract Oral medications available for Parkinson's disease require multiple administrations, which significantly affects the plasma concentration of the drug, and...

Abstract Objective: This study aimed to develop an oral celastrol-loaded self-microemulsifying drug delivery system (Cel-SMEDDS) to enhance the therapeutic efficacy...

Abstract Background: Rebamipide (REB) is a poorly water-soluble drug with limited ocular bioavailability, necessitating advanced delivery strategies for sustained therapy in...

Abstract Background: Inflammation is a complex biological response associated with various pathological conditions, necessitating the development of effective and safer...

Abstract Black Sticky Rice Extract (BSRE; Oryza sativa var. glutinosa Blanco) is rich in anthocyanins and flavonoids with well-documented antioxidant...

Abstract Preservatives are critical for preventing microbial contamination in multi-dose biologics, yet their compatibility with proteins poses a major challenge....

Abstract Macrophages, as cells of the innate immune response, are involved in the pathology of various medical conditions (tumors, intracellular...

Abstract Contemporary small-molecule drug candidates increasingly have limited aqueous solubility, rendering oral delivery challenging. Amorphous solid dispersions (ASDs) and lipid-based...

Abstract Ulcerative colitis (UC) is a chronic inflammatory bowel disease with no curative therapy. Hesperidin (HDN) exhibits potent anti-inflammatory and...

Abstract Introduction Therapeutic proteins are crucial in the treatment of a wide range of diseases. However, the proteins are sensitive...