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Abstract Dapivirine (DPV) is an antiretroviral drug used for prevention of sexually acquired HIV infection in the form of a...
Abstract Oral medications available for Parkinson's disease require multiple administrations, which significantly affects the plasma concentration of the drug, and...
Abstract Objective: This study aimed to develop an oral celastrol-loaded self-microemulsifying drug delivery system (Cel-SMEDDS) to enhance the therapeutic efficacy...
Abstract Background: Rebamipide (REB) is a poorly water-soluble drug with limited ocular bioavailability, necessitating advanced delivery strategies for sustained therapy in...
Abstract Background: Inflammation is a complex biological response associated with various pathological conditions, necessitating the development of effective and safer...
Abstract Black Sticky Rice Extract (BSRE; Oryza sativa var. glutinosa Blanco) is rich in anthocyanins and flavonoids with well-documented antioxidant...
Abstract Preservatives are critical for preventing microbial contamination in multi-dose biologics, yet their compatibility with proteins poses a major challenge....
Abstract Macrophages, as cells of the innate immune response, are involved in the pathology of various medical conditions (tumors, intracellular...
Abstract Contemporary small-molecule drug candidates increasingly have limited aqueous solubility, rendering oral delivery challenging. Amorphous solid dispersions (ASDs) and lipid-based...
Abstract Ulcerative colitis (UC) is a chronic inflammatory bowel disease with no curative therapy. Hesperidin (HDN) exhibits potent anti-inflammatory and...
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