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AquaSolve HPMCAS is a mixture of acetic acid and monosuccinic acid esters of hydroxypropylmethylcellulose.
AquaSolve HPMCAS is used as a solid dispersion polymer for bioavailability enhancement.of poorly soluble active pharmaceutical ingredients (APIs). The versatility of this polymer in addressing solubility issues is a result of its unique properties. These properties lead to enhanced absorption when HPMCAS-based solid dispersions are dosed orally.
AquaSolve HPMCAS is available in three grades differentiated by degree/ratio of substitution. Each grade is available in two particle sizes. Consult the product data sheet or the excipient information package for further details on specifications. Additional substitution levels and ranges are available upon request. Detailed product information is available in the AquaSolve™ Hydroxypropylmethylcellulose Acetate Succinate Physical and Chemical Properties Handbook:
| Manufacturer |
Ashland |
|---|---|
| Quality |
EP, JP, USP |
| Quantity 1 |
100gr |
| Composition |
Hypromellose Acetate Succinate (HPMCAS), mixture of acetic acid and monosuccinic acid esters of hydroxypropylmethylcellulose |
| Function |
used as an enteric coating polymer and in preparation of sustained drug-release formulations |
| Synonym |
HPMCAS |
