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Kolliphor® RH 40





Kolliphor®  RH 40 is a nonionic solubilizer and emulsifying agent obtained by reacting 40 moles of ethylene oxide with 1 mole of hydrogenated castor oil. The main constituent of Kolliphor®  RH 40 is glycerol polyethylene glycol oxystearate, which, together with fatty acid glycerol polyglycol esters, forms the hydrophobic part of the product. The hydrophilic part consistsof polyethylene glycols and glycerol ethoxylate. Kolliphor®  RH 40 is a white to yellowish paste at 20°C.
  • Widely used and approved solubilizer
  • Particularly suited for aqueous solutions of fat-soluble vitamins
  • Chemically stable and practically tasteless – perfect for oral applications
  • Suitable for SEDDS and SMDDS as It is less digestible in GIT conditions as compare to other unsaturated ethoxylated surfactants

Non-ionic oil-in-water solubilizer and emulsifying agent.

Derived from hydrogenated castor oil and ethylene oxide, Kolliphor® RH40 is used as a non-ionic oil-in-water solubilizer and emulsifying agent. It is particularly suitable for fat-soluble vitamins and demonstrates exceptional chemical stability. This tried-and-trusted solubilizer scored highest on resistance to enzymatic digestion in a study of various surfactants, highlighting its potential to enhance patient safety. Kolliphor® RH40 is widely used in self-emulsifying drug delivery systems (SEDDS) or microemulsifying systems (SMDDS) in combination with a co-solubilizer and/or co-solvent. What’s more, Kolliphor® RH40 is almost tasteless – making it ideal for oral applications.

Additional information




Ph.Eur., USP-NF




Emulsifier, Plasticization, Solubilizer, Surfactants

Technical Name

PEG-40 Hydrogenated Castor Oi, Polyoxyl castor oil

Documents and Links

Safety Data Sheet Kolliphor RH 40


Technical Information Kolliphor RH 40


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