Back to shop

Parteck® SI 450 (Sorbitol) EMPROVE ESSENTIAL Ph Eur,BP,JSFA,NF,E 420

This product is currently out of stock and unavailable.


Parteck® SI 450 excipient is part of the Parteck® range of functional excipients developed specifically for solid dose applications. It is a directly compressible sorbitol with an excellent tableting behavior and a pleasant mouthfeel and taste. It enables fast disintegration and dissolution, even at high tablet hardnesses. In addition, it is well-suitable for low dose API formulations as it supports a good content uniformity. As Emprove® Essential excipient, it is a high quality pharmaceutical excipient, offered with extensive documentation facilitating compliance, full supply chain transparency and risk mitigation.

Parteck® SI, directly compressible sorbitol, is available in a variety of particle sizes and has qualities that make it suitable for any application. The unique particle structure of Parteck® SI gives it distinctive physical properties, making it the perfect excipient for combining many ingredients into one elegant and robust tablet formulation.


  • Excellent direct compression properties
  • High dilution and adsorption capacity
  • Larger and highly structured surface area
  • Low hygroscopicity
  • Low amount of reducing sugars
  • Emprove® documentation and regulatory support

We offer several special grades of Parteck® SI with varying particle sizes and qualities designed to meet your applications’ specific requirements.

Parteck® SI: Unique Structure, Outstanding Features

The filamentous and porous surface of Parteck® SI enables more homogenous powder blends, more uniform content, and less dust during manufacture.

Tablets manufactured with Parteck® SI show much slower water uptake than tablets made with standard sorbitol. Its outstanding features – including good flow and excellent mouthfeel – make Parteck® SI the right choice for sugar-free chewables, effervescent tablets and lozenges.

All Parteck® SI products belong to our Emprove® program that provides exceptional documentation to smooth your approval preparation and bring your product to market faster.

Important manufacturer information:
The product will not longe be sampled

Additional information


Merck KGaA









Dosage Form

Capsules, Chewable tablets, dry suspensions, dry syrups, Effervescent tablets, Granules, Lozenges, Oral Suspensions, oral syrups, solid formulation, solid oral, Tablets


Diluent/filler for solid oral formulations, optimized for direct compression

Documents and Links

Safety Data Sheet for Parteck® SI 450 (Sorbitol) 103557


You may also like…

Parteck® SI 400 (Sorbitol) EMPROVE ESSENTIAL Ph Eur,BP,JSFA,NF,E 420

Merck KGaA Select options

Parteck® SI 150 (Sorbitol) EMPROVE® ESSENTIAL Ph Eur,BP,JP,NF,JSFA,E 420

Merck KGaA Select options

Parteck® SI 200 (Sorbitol) EMPROVE ESSENTIAL Ph Eur,BP,JSFA,NF,E 420

Merck KGaA Select options