Solubilizer

Abstract Olanzapine (OLZ) is classified as a typical antipsychotic drug utilized for treatment of schizophrenia, it possesses poor oral bioavailability...

Abstract Background/Objectives: In this study, we present a green, scalable platform for the production of water-dispersible powders co-encapsulating the lipophilic...

Abstract Aim Quercetin is a natural dietary compound known for its potential to prevent chronic diseases. However, the translation of...

Abstract α-Lipoic acid (LA), a naturally occurring antioxidant and anti-inflammatory agent, has limited aqueous solubility and bioavailability which hinders its...

Abstract Nanotechnology has revolutionised pharmaceutical sciences, with mesoporous silica nanoparticles (MSNs) extensively studied as drug carriers. However, their clinical translation...

Abstract Purpose Posaconazole (POS) is widely used as an antifungal agent effective against Candida infections. Because of its very low...

Abstract Fenbendazole (FBZ), a benzimidazole-carbamate anthelmintic, shows promising chemotherapeutic properties. However, it is a poorly water-soluble molecule, leading to low...

Abstract Most novel active pharmaceutical ingredients have low water solubility; therefore, solubility-enhancing methods are applied. The aim of the present...

Abstract Cyclodextrins (CDs) play a crucial role in pharmaceutical formulations due to their unique ability to form inclusion complexes with...

This poster was presented at the ECP 2025 in Porto Introduction Hot melt extrusion (HME) is generally applied for the...