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Abstract Purpose To overcome the strong inter-particulate interactions between the drug and carrier in dry powder inhalers (DPIs), an amorphous...
Abstract Despite their widely recognized performance-related benefits, nanosuspensions (NSs) present major challenges, mainly due to their poor stability during storage....
The Oral Drug Delivery Landscape As drug discovery pushes into new therapeutic frontiers, the task of developing effective, patient-friendly oral...
Abstract There is a growing demand in the subcutaneous delivery of monoclonal antibodies (mAbs) to reduce treatment burden for both...
Abstract Hygroscopicity poses a significant challenge in the formulation of pharmaceutical and nutraceutical products, as moisture absorption often leads to...
From Milk to Medicine: 100 Years of Pharmaceutical Lactose continuous improvement For more than a century, lactose has quietly shaped...
Abstract The therapeutic landscape for biologics is rapidly transitioning from intravenous (IV) to subcutaneous (SC) administration, offering significant benefits in...
Abstract Spray dried dispersion (SDD) is increasingly used in solid dose formulations for poorly soluble active pharmaceutical ingredients (APIs). Dissolution...
Abstract The design of free-flowing lyophilized powders by spray-freeze-drying (SFD) enables novel therapeutic applications, including nasal administration. In this study,...
Abstract Aqueous colloidal dispersions of water-insoluble polymers (APDs) —commonly referred to as pharmaceutical latexes or pseudolatexes— are extensively employed in...
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