Spray drying

Abstract There is a growing demand in the subcutaneous delivery of monoclonal antibodies (mAbs) to reduce treatment burden for both...

Abstract Hygroscopicity poses a significant challenge in the formulation of pharmaceutical and nutraceutical products, as moisture absorption often leads to...

From Milk to Medicine: 100 Years of Pharmaceutical Lactose continuous improvement For more than a century, lactose has quietly shaped...

Abstract The therapeutic landscape for biologics is rapidly transitioning from intravenous (IV) to subcutaneous (SC) administration, offering significant benefits in...

Abstract Spray dried dispersion (SDD) is increasingly used in solid dose formulations for poorly soluble active pharmaceutical ingredients (APIs). Dissolution...

Abstract The design of free-flowing lyophilized powders by spray-freeze-drying (SFD) enables novel therapeutic applications, including nasal administration. In this study,...

Abstract Aqueous colloidal dispersions of water-insoluble polymers (APDs) —commonly referred to as pharmaceutical latexes or pseudolatexes— are extensively employed in...

Abstract Background/Objectives: Cannabidiol (CBD) has emerged as a potential therapeutic agent for respiratory disorders, including asthma and chronic obstructive pulmonary...

Abstract Background/Objectives: The development of dry powder formulations for pulmonary delivery of therapeutic antibodies requires careful stabilization strategies to preserve...

Abstract Hypothesis During spray freeze drying (SFD), vitrification, recrystallization, and polymorphic transitions govern particle morphology and mechanical integrity. We hypothesize...