Designing highly porous amorphous celecoxib particles by spray freeze drying leads to accelerated drug absorption in-vivo

30. March 2022

Poorly water-soluble drugs are still a major challenge to overcome in order to achieve sufficiently high oral bioavailability. Spray freeze...

SEM images of raw and spray-dried samples at a magnification of ivermectin

Preparation and Characterization of Inhalable Ivermectin Powders as a Potential COVID-19 Therapy

15. March 2022

Ivermectin has received worldwide attention as a potential COVID-19 treatment after showing antiviral activity against SARS-CoV-2 in vitro. However, the...

SEM micrographs of dry placebo and ibuprofen-loaded PECs obtained by spray-drying and ambient-drying.

Influence of spray-drying process on properties of chitosan/xanthan gum polyelectrolyte complexes as carriers for oral delivery of ibuprofen

27. February 2022

Polyelectrolyte complexes (PECs) are attractive carriers with recognized potential to enhance oral delivery of poorly soluble high-dosed low-molecular-weight drugs. The...

Liquisolid systems: Evaluation of the influence of formulation variables on the optimum liquid load

25. February 2022

Liquisolid systems represent an emerging approach in the preparation of solid dosage forms with liquid lipophilic drug or poorly water-soluble...

Spray Drying and Particle Engineering in Dosage Form Design for Global Vaccines

22. February 2022

Vaccines are a very important tool in the effort to reduce the global burden of infectious diseases. Modern vaccines can...

Development of a novel rapamycin loaded nano- into micro-formulation for treatment of lung inflammation

22. February 2022

It has recently emerged that drugs such as the mTOR inhibitor rapamycin (Rapa) may play a key role in the...

Solubility enhancement – The Interview with Fuji Chemical

22. February 2022

Fuji Chemical Industries specializes in producing porous spray-dried excipients for the pharmaceutical and nutraceutical markets. They spray-dry their excipients to...

graphical abstract of Experimental Design and Optimization of a Novel Dual-release Drug Delivery System With Therapeutic Potential Against Infection With Helicobacter pylori

Experimental Design and Optimization of a Novel Dual-release Drug Delivery System With Therapeutic Potential Against Infection With Helicobacter pylori

17. February 2022

The objective of this study was to develop clarithromycin-loaded lipid nanocarriers and incorporate them into microcapsules for pH-specific localized release...

Solubility enhancement – Transform insoluble drugs into stable and efficient formulations

15. February 2022

Recent industry trends show many pharmaceutical manufacturers are creating drugs with greater degrees of lipophilicity, higher molecular weight, greater physical...

Factors Influencing the Crystallization-Onset Time of Metastable ASDs

2. February 2022

In formulation development, amorphous solid dispersions (ASD) are considered to improve the bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs)....

Spray drying