ADM

Sesame oil is well known in kitchens for its rich flavor and health benefits—but pharmaceutical use requires far more than taste. Refined Sesame Oil IV-1 is a highly specialized excipient designed for strict pharmaceutical standards where purity, consistency, and stability are non-negotiable. This…
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Abstract The present study focuses on the development and optimization of a solid self-microemulsifying drug delivery system (SSMEDDS) of Nateglinide, a poorly water-soluble antidiabetic drug, to enhance its oral bioavailability. Initially, a liquid SMEDDS was formulated using Capmul MCM as the…
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While extra virgin olive oil is prized in kitchens, it falls short in pharmaceutical use. Refined Olive Oil IV is specially processed to meet strict standards for purity, stability, consistency—making it ideal for high-quality drug formulations. From its controlled composition to pharmacopeial…
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Abstract Alzheimer's disease (AD) is a complex neurodegenerative that affects over 55 million people worldwide, a number expected to double by 2050 due to aging populations. This growing prevalence imposes immense societal and economic burdens on healthcare systems and caregivers. AD is challenging…
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This year´s Vitafoods Europe opens its doors in Barcelona at Fira Barcelona Gran Via. From 20th to 22th May you can have a face-to-face chat with visitors and exhibitors again. PharmaExcipients gives you an overview of the excipient suppliers, their booths, main topics and products in the…
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Abstract The main purpose of this study was to design and develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) for the oral administration of benidipine (BD) and telmisartan (TEL) using the adsorption method with eucalyptus oil, Transcutol P, and Kolliphor EL via the Box–Behnken…
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Abstract Since the FDA approval of the first nanodrug Doxil® in 1995, twenty subsequent liposome-and lipid nanoparticle (LNP) based drugs (of which 10 are nanodrugs), were approved by the FDA. The application of such drug-products was considerably boosted by the mRNA-LNP based vaccines used to stop…
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Abstract Hypothesis Oral delivery of the proliferation-inhibiting brain acid-soluble protein 1 effector domain peptide (Myr-NT) towards MYC-dependent gastrointestinal tumors can be achieved by forming hydrophobic ion pairs (HIPs) and incorporating them into lipid-based formulations.…
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Abstract Aims A new self-nanoemulsifying drug delivery system (SNEDDS) was developed for erlotinib (Ert) oral delivery. Highlights A pseudo-ternary phase diagram for olive oil, Tween 80 and PEG 600 was constructed. A SNEDDS composed of 10% olive oil, 20% Tween 80 and 70% (V)…
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Abstract Poor water solubility remains a significant challenge in the pharmaceutical industry that limits the therapeutic efficacy and bioavailability of many active pharmaceuticals. Soluplus® (SLP), an amphiphilic graft copolymer made of polyethylene glycol, polyvinyl caprolactam, and polyvinyl…
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