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ADM
Quality by design aided self-nano emulsifying drug delivery systems development for the oral…
The primary objective of the research effort is to establish efficient solid self-nanoemulsifying drug delivery systems (S-SNEDDS) for benidipine (BD) through the systematic application of a quality-by-design (QbD)-based paradigm. Utilizing Labrafil M 2125 CS, Kolliphor EL, and Transcutol P, the…
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Topical delivery of nanoemulsions for skin cancer treatment
Skin cancer chemotherapeutics often lead to the development of severe cytotoxicity, compelling the development of novel delivery systems to not only enhance therapeutic efficacy but also minimize side effects and improve patient compliance. In recent years, topical nanoemulsions have emerged as…
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Development and Evaluation of a Self-Nanoemulsifying Drug Delivery System for Sinapic Acid with…
This study aimed to develop a self-nanoemulsifying drug delivery system (SNE) for sinapic acid (SA) to improve its solubility and antiviral activity. Optimal components for the SA-SNE formulation were selected, including Labrafil as the oil, Cremophor EL as the surfactant, and Transcutol as the…
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Bioactive chemlali olive derivatives and compounds useful for pharmaceutical purposes: A review
Several articles in the literature deal with and analyze components extracted from the olive tree, but these researches are mainly focused on the quality of olive oil and more precisely its volatile components, often related to their antioxidant properties, which denies other derivatives of the…
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Nanoemulsions as a Promising Carrier for Topical Delivery of Etodolac: Formulation Development and…
Abstract
This research primarily focuses on the development of innovative topical nanoemulsions for etodolac, aimed at surmounting its inherent limitations. The preparation of etodolac nanoemulsions is accomplished through a combination of high shear homogenization and ultrasonication methods. The…
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Topical Delivery of Terbinafine HCL Using Nanogels: A New Approach to Superficial Fungal Infection…
This study investigated pH-responsive Terbinafine HCL (TBH)-loaded nanogels as a new approach to treating superficial fungal infections. Acrylic acid (AA) is a synthetic monomer that was crosslinked with a natural polymer (gelatin) using a free radical polymerization technique to fabricate…
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Smart nano-in-microparticles to tackle bacterial infections in skin tissue engineering
Chronic wounds (resulting from underlying disease, metabolic disorders, infections, trauma, and even tumours) pose significant health problems. In this work, microparticles, based on polysaccharides (maltodextrin or dextran) and amino acids, and doped with antibacterial nanoparticles (CuO or ZnO…
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Extemporaneous preparation of paediatric oral formulations with sildenafil citrate
The paediatric population is composed of several very diferent subgroups, each with its own specifc characteristics. For this reason, children cannot be considered “small adults”. The development of formulations suitable for children is a complex process, as it must consider the physiological…
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A novel cationic arginine-modified Self-Nanoemulsifying drug delivery system (SNEDDS) for improved…
Abstract
Naringin (NRG) is a flavonoid derived from citrus fruits. Despite its pharmacological significance, NRG's therapeutic effectiveness is constrained by its unusual physicochemical characteristics, such as its lower aqueous solubility. This study was intended to develop an alkylated arginine…
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CPHI Barcelona 2023 – with a focus on excipients
This year CPHI Europe opens its doors in Barcelona at Fira Barcelona Gran Via.
From 24th to 26th October you can have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack,
P-MEC, FDF, ICSE and BioProduction will be held together with CPHI.
Pharma Excipients gives you an…
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