Captisol

AAPS PharmSci 360 brings the pharmaceutical science community to New Orleans from 25 to 28 October 2026. For anyone working...

Abstract JDS364.HCl, an oxime-based reactivator developed for the treatment of organophosphorus nerve agent intoxication, has recently emerged as a promising...

Abstract Poor aqueous solubility is a major cause of solubility-limited absorption and misleading pharmacokinetic outcomes during early oral drug discovery....

This year CPHI Europe opens its doors in Milan at Fiera Milano. From 6th to 8th October you can have a...

Abstract Fungal keratitis (FK) is a leading cause of corneal blindness worldwide. Although voriconazole (VOR) is effective, its poor corneal...

What are “enteric coated” capsules and why are they used? Enteric coating refers to a dosage form (e.g. capsule) of...

Abstract The beneficial effect of bedaquiline fumarate (BQF) for tuberculosis (TB) is limited by its oral bioavailability, which is very...

Abstract This research evaluated the viability of powder discharge-based KinetiSol (pKSD) as a rapid, solvent-free particle engineering technology for producing...

Abstract In this research, with the aim of improving the solubility and bioavailability of famotidine, the inclusion complex of famotidine...

Abstract Background: The key parameters determining the bioavailability of an active pharmaceutical ingredient are its solubility/dissolution rate in physiological fluids...