Dr. Paul Lohmann

Abstract Much of the remarkable advancements in oral peptide delivery have been achieved through the use of chemical permeation enhancers,...

Abstract Oral administration of solid dosage forms for delivery of therapeutic peptides is highly desired. Preclinical investigations on co-administration with...

Abstract Polysaccharides and starch derivatives can play a role in the development of buccal film and patches. Buccal films are...

Abstract The study of extractables and leachables has become increasingly important in the pharmaceutical industry, with growing concerns about minimizing...

Abstract Aqueous solubility is a crucial physicochemical property influencing drug absorption and bioavailability. Current solubility assays, whether assessing thermodynamic or...

Dr. Paul Lohmann presents two focus areas for their CPhI Frankfurt booth: Mineral Salts as APIs  The Dr. Paul Lohmann...

Abstract Lornoxicam, a potent nonsteroidal anti-inflammatory drug (NSAID), suffers from poor aqueous solubility, leading to limited dissolution and variable bioavailability....

Abstract Localized vaginal drug delivery can offer safer and more effective treatment options for various conditions, also for pregnant women....

Abstract Sodium caprate (C10) is the most investigated permeation enhancer to promote oral peptide absorption. However, the clinical translation of...

Abstract Poly-2-hydroxypropane-1,2,3-tricarboxylic carubin (P-2HTCb) has characteristics as a glidant similar to talc and magnesium stearate (MgSt), such as irregular shape,...