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Abstract The dynamic and transitory nature of the distal small intestine makes targeted drug delivery to this region particularly challenging....

Abstract The commercial implementation of continuous granulation requires an intelligent control framework compliant with Quality by Design (QbD) principles. To...

Abstract Purpose: To formulate enteric-coated osmotic tablets for colon-targeted delivery of hydrocortisone. Methods: Nine core tablet batches were prepared with...

Abstract Amorphous solid dispersions (ASDs) are widely used to enhance the solubility of poorly water-soluble drugs. Among commercial manufacturing approaches,...

Abstract Background/Objectives: For hyperlipidemic patients with statin resistance, a fixed-dose combination of a non-statin drug such as ezetimibe (EZT) and...

Abstract Background: Fused deposition modeling (FDM) is one of the most well-known and often published methods for 3D-printed drug delivery systems....

Abstract Background/Objectives: Rebamipide is a gastroprotective agent with poor aqueous solubility and rapid gastrointestinal clearance, leading to reduced therapeutic efficiency. This...

Abstract The shelf life of pharmaceutical products depends on the stability of active pharmaceutical ingredients in the presence of other...

Abstract Bulk density (ρb) serves as a fundamental powder parameter across various industries. In the pharmaceutical industry, its implications on...

Abstract As precision medicine advances, the need for customizable drug delivery systems has become increasingly important. In this study, we...