PMC Isochem

Abstract Poor water solubility remains a significant challenge in the pharmaceutical industry that limits the therapeutic efficacy and bioavailability of...

Abstract Pharmaceutical excipients such as P-glycoprotein inhibitors can also increase the solubility and affinity of drugs to the intestinal membrane,...

Abstract Lung cancer ranks among the leading factors behind cancer-related fatalities across the globe. Erlotinib (ERT) is one of the...

Abstract Purpose Ovarian cancer (OC) is difficult to detect early; therefore, it is highly likely to advance to peritoneal metastasis...

Abstract Poor solubility of many drugs, with ensuing low bioavailability, is a big challenge in pharmaceutical development. Nanosuspensions have emerged...

Abstract Curcumin (CUR), a polyphenolic pigment of turmeric, -possess biological and medicinal properties. Regardless of having a wide range of...

Abstract For compendial dissolution testing of solid dosage forms, media volumes of 500 to 900 mL are used in apparatus...

Abstract There is a growing pharmaceutical interest in supersaturated lipid-based formulations (Super-LbF) as an innovative strategy to enhance drug loading...

Abstract Coenzyme Q10 (CoQ10) is a lipophilic antioxidant agent that plays a crucial role in the mitochondrial electron transport chain....

Abstract Ulcerative colitis (UC) is a prevalent inflammatory bowel disease, and conventional treatments, such as anti-inflammatory medications and surgery, often...