Surfactants

Background Berberine is an isoquinoline alkaloid with potent anti-inflammatory effects. However, its therapeutic efficacy is often restricted by its poor...

Abstract Dasatinib (DASA), a potent second-generation multitarget kinase inhibitor marketed as Sprycel® (Tablet), is limited by poor oral bioavailability (14–24 %)...

Abstract Amphotericin-b (AmB) is a broad-spectrum polyene macrolide antifungal and anti-Leishmaniosis. We addressed HSPiP and QbD (quality by design) oriented...

Our industry experts Dr. Sreejit Menon and Dr. Stephen Rumbelow recently contributed to a chapter in: Surfactants in Biopharmaceutical Development....

Abstract Oral bioavailability of nebivolol (NEB), a highly-selective β1-adrenergic receptor antagonist specially used in hypertension treatment, is limited by its...

Abstract Preclinical testing of new drug candidates frequently necessitates high-dose solution formulations to support robust testing in rodent models. This...

In this study, the interaction among multifunctional excipients, including polysaccharides, cellulose derivatives, and surfactants, was particularly investigated, together with its...

Croda announces the launch of their newest bioprocessing solution, developed to overcome batch-to-batch variation challenges in mammalian cell culture, offering...

Abstract The use of lipid nanocarriers as components of cosmetic formulations may provide an opportunity to fully exploit the beneficial...

This study aims to enhance the solubility of Olaparib, classified as biopharmaceutical classification system (BCS) class IV due to its...