Tag: formulation

Understanding the Risks Associated with Nitrosamines Nitrosamines have become a major concern in the pharmaceutical industry since their detection in ...

Abstract Novel bitter-taste-masking microparticles for loading in orally disintegrating (OD) tablets have been developed using a mechanical powder processor. Swellable ...

Amphiphilic, non-ionic block copolymers suitable for diverse pharmaceutical applications Did you know? Kolliphor® P grade poloxamers are among the most ...

Abstract Bottom-spray Wurster fluidized-bed coating is widely used to produce controlled-release urea; however, coating quality depends not only on thermal ...

Abstract Biomacromolecules including peptides, proteins, antibodies, and gene medicines, comprise important classes of therapeutics in treating disease. A drawback of ...

Abstract Entacapone is a catechol-O-methyltransferase (COMT) inhibitor, widely used for the symptomatic treatment of Parkinson’s disease. However, it presents setbacks ...

Abstract Background/Objectives: The objective of this study was to design and optimize a continuous wet granulation process for Amiodarone hydrochloride ...

Abstract This research evaluated the viability of powder discharge-based KinetiSol (pKSD) as a rapid, solvent-free particle engineering technology for producing ...

Abstract Background Diosgenin (DG) is a steroidal sapogenin derived from medicinal plants such as Dioscorea nipponica, Smilax china, and Trigonella foenum-graecum. DG exhibits ...

Abstract Background: Hot-melt extrusion (HME) is a promising technology for the manufacturing of drug products; however, its application is limited by ...