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New product – Kleptose F 7% – BETA CYCLODEXTRIN
Kleptose F 7% - BETA CYCLODEXTRIN
Roquette presents a new product:
KLEPTOSE® F 7% – EXP β-cyclodextrin for oral dosage forms contains less than 7% of water. It is well suited for dry processing techniques, such as direct compression, where its low water content benefits moisture-sensitive APIs and formulations (e.g., ODTs, chewables, effervescent tablets) while offering enhanced stability, solubility, and taste masking through molecular encapsulation.
Kleptose F 7% – BETA CYCLODEXTRIN
- Excellent tabletability across a range of compression forces and speed
- Moisture protection, reducing degredation in moisture sensitive formulations
- Consistent particle size distribution to enhance processability
Product information
| Product Name | KLEPTOSE® F 7% – BETA CYCLODEXTRIN |
| Generic Name | Betacyclodextrin |
| Physico-chemical properties | |
| Compliance | EP/USP-NF/IP |
| Synonyms | Beta-cyclodextrin |
| CAS Number | 7585-39-9 |
| Physical Form or Appearence | White or almost white crystalline powder |
| Water content (LOD) | Water Content (LOD) Maximum: 7 % |
| Average mean particle diameter | 40 µm |
| Particle Size Distribution by Laser Diffraction | dv10: 10 µm
dv50: 40 µm dv90: 96 µm |
| Solubility | Solubility in water: 18.5 g/l. Practically insoluble in ethanol (95 %). |
Water sorption isotherm at 20°C
Tablet hardness
| Experimental Conditions for Compression Behavior | Tablet Press: STYL’ONE EVO
Production Speed: 50 RPM (linear punch velocity: 70 mm/s; simulated KORSCH XL-400 rotary press speed: 105,000 tablets/hour); 20% pre-compression force Tooling: Diameter 10 mm R10 concave Formula: 5% API / 25% KLEPTOSE® F 7% – EXP beta-cyclodextrin / 69% PEARLITOL® 100 SD mannitol / 1% Roquette Magnesium Stearate Tablet Mass: 400 mg |
| Powder Characteristics | Bulk Density: 0.53 g/cm3
Tapped Density: 0.76 g/cm3 True Density: 1.48 g/cm3 |
Read more here
Source: Roquette, website KLEPTOSE® F 7% – EXP β-cyclodextrin
Roquette Pharma Solutions
Imagine a world where every person leads a healthy life and can look forward to a healthy future. This is our driving vision at Roquette Pharma Solutions.
Combing the very best of nature with cutting-edge scientific research, we develop pharmaceutical technologies that improve, sustain and save lives worldwide.
Our large, diverse and vertically integrated portfolio of sustainable excipients, nutraceutical active ingredients and APIs help us redefine what’s possible in drug development.
We are solution-orientated. We are innovative. We are your expert formulation partner.
Together, we can solve the toughest challenges in drug delivery.
Are you ready to start your journey?
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