High-shear (HS) melt granulation and hot melt extrusion (HME) were compared as perspective melt-based technologies for preparation of amorphous solid...

Polysorbate 80 (PS80) is employed as a cryoprotectant in biotherapeutic formulations to preserve biologics from denaturation during the freezing process....

Abstract It is necessary to use a scientifically sound process for excipient risk evaluation, selection, and management in order to...

Twin-screw wet granulation (TSG) is a continuous manufacturing technique either for granules as final dosage form or as an intermediate...

Abstract Roller compaction is a widely used continuous dry granulation process in the food and pharmaceutical industries. The flow and...

Abstract Considering the strong dependence of agglomerate characteristics on various operating parameters, this study employs the control variable methodology (CVM)...

Introduction We are Sigachi, a leading name in the world of Microcrystalline Cellulose (MCC) manufacturing tailored for Pharmaceutical applications. With...

Twin-screw melt granulation (TSMG) is one of the promising green technological approaches for the manufacturing of solid dosage forms of...

Tablet disintegration is crucial for drug release and subsequent systemic absorption. Although factors affecting the disintegrant’s functionality have been extensively...

Abstract Drug substances and excipients must be stored in recommended storage conditions and should comply with their specifications during the...