Nomisma Healthcare

Company profile

Global Partner in Bioresorbable Polymers for Pharmaceuticals, Medical Implants, Tissue Engineering, and Cosmetic Industries

Nomisma Healthcare, a renowned leader in manufacturing Lyophilized, Tin Free and sterilized PLGA & PLA polymers. With a strong emphasis on quality and innovation, we specialize in producing high-grade polymers that cater to the diverse needs of the healthcare industry.

Innovative Manufacturing

Nomisma Healthcare takes pride in its state-of-the-art manufacturing facilities and advanced research capabilities, enabling us to deliver exceptional Lyophilized Tin Free and sterilized PLGA and PLA polymers. Our commitment to excellence ensures that our polymers meet the stringent standards of purity, sterility, and performance required for biomedical applications.

Serving Diverse Industries

As a trusted partner to pharmaceutical companies and medical device manufacturers, we provide reliable and customizable polymer solutions that enable precise drug release and enhance therapeutic efficacy. By choosing Nomisma Healthcare, you gain access to top-tier polymers that can revolutionize controlled release drug delivery and elevate the quality of patient care.

Advantages of Nomisma’s Polymers

At Nomisma Healthcare, we are dedicated to providing not only exceptional polymer products but also the comprehensive support you need to bring your innovations to life. Whether you require a custom-designed polymer tailored to your specific application or access to essential technical resources, we are here to empower your research and development.

• Superior quality and purity: Our polymers meet the highest purity standards for biomedical applications. Rigorous quality control ensures reliable, consistent materials for your critical projects.
• Versatile & customizable solutions: Tailor polymers to your specific needs with our versatile solutions. We customize degradation rates, strength, and release profiles for diverse applications.
• Enhanced biocompatibility & Safety: Ensure safety with our biocompatible, sterilized polymers. Extensive studies confirm minimal adverse reactions, providing confidence in your products.
• Controlled release capabilities: Achieve precise drug release with our advanced polymers. Optimize dosing and enhance patient compliance through controlled therapeutic effects.
• Collaborative partnership & support: Partner with our experts for comprehensive support. We provide technical assistance and customization guidance to ensure successful integration of our polymers.

Key Product Category

1. Poly(lactic-co-glycolic acid) | PLGA | CAS 26780-50-7

Poly(lactic-co-glycolic acid), commonly known as PLGA, is the globally recognized “gold standard” among FDA-approved biodegradable and biocompatible polymers. Extensively utilized in novel drug delivery systems, PLGA offers unparalleled versatility for controlled-release formulations, making it the excipient of choice for next-generation pharmaceuticals, medical devices, and biotech innovations.

At Nomisma Healthcare, we manufacture ultrapure, lyophilized PLGA polymers engineered to meet the most rigorous demands of global pharmaceutical excellence. Whether you are developing long-acting injectables, targeted nanoparticles, or resorbable implants, our USP-recognized PLGA ensures safety, efficacy, and regulatory compliance.

Why Choose Nomisma Healthcare’s PLGA?

As a trusted leader in high-purity biodegradable excipients, we go beyond standard manufacturing. Our PLGA is designed to give formulators complete control over drug release kinetics and product stability.

• USP-Recognized Quality:Our polymers align with United States Pharmacopeia (USP) standards, and we provide comprehensive USP reverse engineering data to accelerate your regulatory filings.
• Unmatched Purity & Safety:We offer industry-leading low residual tin (≤ 50 ppm typical) using Sn-based catalysts, alongside specialized Tin-Free options for highly sensitive formulations.
• Advanced Grading:Choose from Sterile-grade and Low Bacterial Endotoxin options specifically designed for injectable depots and implantable medical devices.

Total Customization: From tailored molecular weights to controlled block lengths and copolymer ratios, we engineer the polymer to fit your exact drug delivery profile.

2. Polylactide | Polylactic Acid (PLA) | CAS 26100-51-6

Polylactide, widely recognized as Polylactic Acid (PLA), is a highly versatile, biodegradable, and biocompatible aliphatic polyester. Sourced from renewable resources, our premium-grade PLA (CAS No. 26100-51-6) is engineered for a wide array of applications, ranging from advanced biomedical devices and drug delivery systems to 3D printing and sustainable packaging.

Whether you require specific molecular weights, specialized end groups, or sterile-grade materials for medical use, our customizable PLA solutions are designed to meet the rigorous demands of modern research and manufacturing.

3. Polycaprolactone | Poly(ε-caprolactone) (PCL) | CAS 24980-41-4

Polycaprolactone (PCL) Polymer is a highly versatile, semi-crystalline, and fully biodegradable aliphatic polyester. Renowned for its exceptional flexibility, low melting point, and remarkably slow degradation rate, PCL has become a cornerstone material in advanced biomedical and industrial applications. Whether you are developing long-term medical implants, engineering controlled drug delivery systems, scaffolding for tissue engineering, or innovating in the 3D printing space, our medical-grade PCL delivers the reliability and performance your project demands.

Key Applications of Polycaprolactone (PCL)

• Long-Term Implants:With a degradation time of up to 2–4 years, PCL is ideal for long-term resorbable sutures, bone fixation devices, and orthopedic implants that require sustained mechanical support.
• Drug Delivery Systems:The slow hydrolytic degradation of PCL allows for highly controlled, sustained, and localized release profiles for therapeutic agents and pharmaceuticals.
• Tissue Engineering:Highly biocompatible and easily processable, PCL serves as an excellent structural scaffold for cell growth, skin grafts, and regenerative medicine.
• 3D Printing & Additive Manufacturing:Boasting a low melting point (~60°C) and excellent melt-flow properties, PCL is a favorite for FDM 3D printing, shape-memory polymers, and rapid prototyping of medical devices.

4. Monomers

Nomisma Healthcare is a premier global supplier of pharmaceutical-grade cyclic monomers, specifically engineered for advanced Ring-Opening Polymerization (ROP). Our portfolio features ultra-high purity L-Lactide, DL-Lactide, and Glycolide. Manufactured in a state-of-the-art GMP facility, our monomers are the foundational building blocks for synthesizing high-molecular-weight biodegradable polymers such as PLLA, PDLLA, and PLGA. With exceptional batch-to-batch consistency and specialized moisture-proof packaging, our monomers can be directly used in ROP processes without the need for further purification.

Advantages for High-Molecular-Weight Polymer Synthesis

• Optimized for Direct ROP Usage: strictly controlled water content of below 200 ppmand an acid number of below 1 ppm. This ultra-low impurity profile makes them ideal for high-molecular-weight ROP, allowing chemists to use the product directly in the reactor without any time-consuming further purification or drying steps
• GMP Facility & Reliable Capacity: Manufactured in a dedicated, strictly controlled GMP facility, we guarantee pharmaceutical-grade quality and traceability. We maintain a dedicated, reliable production capacity of 10 Metric Tons (mT) per year, ensuring uninterrupted supply for both R&D scale-up and commercial manufacturing.

5. Block CoPolymers

Advanced Amphiphilic Block Copolymers for Next-Generation Drug Delivery & Biomaterials

Leading supplier of precisely engineered, pharmaceutical-grade block copolymers, including PLGA-PEG, PLA-PEG, and PCL-PEG di- and triblock architectures. By covalently linking hydrophobic biodegradable segments (e.g., PLGA, PLLA, or PCL) with hydrophilic polyethylene glycol (PEG) chains, we provide formulators with smart, amphiphilic materials. These polymers spontaneously self-assemble in aqueous environments, making them the gold standard for micellar drug delivery, stealth nanoparticles, in-situ forming hydrogels, and advanced surface modifications, as extensively validated in contemporary pharmaceutical literature.

Target Applications for Amphiphilic Block Copolymers

*Polymer architectures, block lengths, and end-group functionalities can be custom-synthesized to meet precise critical micelle concentration (CMC) and degradation requirements. Refer to our custom synthesis capabilities for details.

6. Poly(glycolide-co-ℇ-caprolactone) | PGCL | CAS No 24980-41-4

7. Poly(L-lactide-co-ℇ-caprolactone) | PLA-PCL

8. Poly(DL-lactide-co-ℇ-caprolactone) | DLPLA-PCL

9. Premium Porous & Fluffy Microspheres (<50 µm) for Aesthetics, Tissue Engineering & 3D Printing

Nomisma Healthcare supplies advanced, sub-50-micron porous and fluffy microspheres manufactured from high-purity PLLA, PDLLA, PCL, and PLGA. Specifically engineered to overcome sedimentation challenges in viscous carrier gels, these highly porous particles are the gold standard for next-generation aesthetic cosmetic dermal fillers, regenerative tissue engineering scaffolds, and high-resolution 3D printing bioinks. We provide comprehensive batch documentation, including Particle Size Distribution (PSD) histograms and high-resolution Scanning Electron Microscope (SEM) imagery, with sterile options available upon request.

*Particle morphology, size distribution, and sterility can be fully customized to match your specific formulation, extrusion, or injection requirements. Contact our technical team for tailored specifications.

SHOP NOMISMA EXCIPIENTS

Brochures

Product catalogue

Contact

Nomisma Healthcare Pvt. Ltd
J-63, B.I.D.C. Industrial Estate,
Opp. Jyoti Switchgear Pvt. Ltd.,
Gorwa, Vadodara 390 016, GJ-India

Email:

[email protected]

[email protected]