Continuous manufacturing

Patients and caregivers experience challenges following a prescribed medicine routine. If the active pharmaceutical ingredients (API) are released quickly then...

Abstract With the implementation of advanced manufacturing concepts (e.g., continuous operation, integration of different process routes and modular manufacturing), control...

Abstract Continuous manufacturing offers advantages over traditional batch methods, including agility, efficiency, and sustainability. However, transitioning to continuous manufacturing in...

Abstract Background/Objectives: The oral delivery of large-molecule drugs remains challenging due to poor solubility, perdemeability, and stability in the gastrointestinal...

Purpose Understanding batch-to-batch variation of excipients and correlating this to process performance is a key concept of Quality-by-Design for pharmaceutical...

Abstract Process analytical technology (PAT) tools are an important part of process monitoring and control in pharmaceutical continuous manufacturing (CM)...

The pharmaceutical industry has been shifting towards continuous manufacturing, specifically for tablet production. Compared to batch processing, continuous tableting exhibits...

Abstract Oral drug delivery remains the preferred method of drug administration but due to poor solubility many active pharmaceutical ingredients...

Abstract In recent years, continuous manufacturing (CM) has become increasingly popular in the pharmaceutical industry for the production of oral...

Abstract Process Analytical Technology (PAT) plays a crucial role in the design of today’s manufacturing lines as continuous manufacturing becomes...