Disintegrant / Superdisintergrant

Abstract Orodispersible tablet is a patient-friendly alternative for delivering the drug to patients having problems with swallowing and sensitive to...

Abstract Amorphous solid dispersion (ASD) is a widely adopted strategy to enhance the solubility of poorly water-soluble drugs. However, disintegration...

Abstract Low water solubility and extensive hepatic first-pass metabolism limit oral bioavailability of Nebivolol hydrochloride (NEB), a new-generation β-blocker agent...

See the latest edition of the Fuji Chemical Technical Newsletter: THE POLYMORPHISM CHALLENGE IN BILASTINE FORMULATION Bilastine is a second-generation,...

Abstract Background: ODT acetaminophen tablets are an alternative drug therapy for patients who have difficulty in swallowing tablets or capsules....

Abstract Orally disintegrating tablets (ODTs) are a solid oral dosage form designed to rapidly disintegrate in the mouth without the...

Highlights In-depth investigation conducted on titanium dioxide free film coated tablets revealed degradation risks from photostability, physical stability and chemical...

Abstract Parkinson’s disease (PD) is frequently complicated by dysphagia, undermining timely and reliable oral dopaminergic medication. Levodopa’s short half-life and...

Abstract Poor aqueous solubility and thereby poor and/or variable bioavailability of drug candidates is frequently overcome by developing enabling formulations...

Abstract The development of robust oral tablet formulations remains time-consuming, often limited by scarce data and the difficulty of incorporating...