Disintegrant / Superdisintergrant

Abstract Atomic layer coating (ALC) is an emerging, solvent-free technique to coat amorphous solid dispersion (ASD) particles with a nanolayer...

Abstract Amorphous solid dispersion (ASD) tablets based on hydrophilic polymer carriers may encounter disintegration challenges. In this work, the effect...

The objective of this study was to examine the impact of the physicochemical properties of the loaded drug or excipient,...

Press Release Wilmington, Del., Oct. 2, 2024 – Ashland is showcasing two new life sciences products during upcoming tradeshows, CPHI...

Pharmaceutical lactose has been used since the 19th century, and has carved out a place for itself in the pharmaceutical...

The oral bioavailability of sildenafil citrate is approximately 43%, primarily limited by the low aqueous solubility and first-pass effect. Considering...

Abstract It is necessary to use a scientifically sound process for excipient risk evaluation, selection, and management in order to...

In this research, 3D-printed antifungal buccal films (BFs) were manufactured as a potential alternative to commercially available antifungal oral gels...

Superdisintegrants and their working mechanisms Disintegrants and superdisintegrants are well-known excipients that are used in the formulation of oral dosage...

Abstract Background: Fenofibrate (FF) is a BCS class II compound whose poor solubility poses challenges in drug delivery and bioavailability. Solid...