Disintegrant / Superdisintergrant

Abstract In recent years, solid dosage forms have gained interest in pediatric therapy because they can provide valuable benefits in...

Tablet disintegration is crucial for drug release and subsequent systemic absorption. Although factors affecting the disintegrant’s functionality have been extensively...

Abstract Montelukast sodium is widely used in treatment of asthma and other allergic disorders. The Montelukast sodium is a water...

Abstract Drug substances and excipients must be stored in recommended storage conditions and should comply with their specifications during the...

In this study, a compartmental disintegration and dissolution model is proposed for the prediction and evaluation of the dissolution performance...

Only few excipients are known to be suitable as pelletization aids. In this study, the potential use of croscarmellose sodium...

Abstract Advanced manufacturing technologies such as continuous processing require fast information on the quality of intermediates and products. Process analytical...

The xerogel pill has been developed as a novel dosage form with dose-adjusting and swallow-assisting functions by using drop freeze-drying...

Abstract Forty-eight (48) drug products (DPs) containing amorphous solid dispersions (ASDs) have been approved by the U.S. Food and Drug...

Abstract The influence of hydroxypropyl cellulose type (HPC-SSL SFP, HPC-SSL), concentration (2 %, 3.5 %, 5 %) and filler (lactose, calcium hydrogen phosphate...