Improving the granule strength of roller-compacted ibuprofen sodium for hot-melt coating processing

25. June 2016

25. June 2016 Abstract Solvent-free hot-melt coating processing is a novel and cost-efficient approach to manufacturing taste-masked multiparticulate systems. However,...

Infacort®, Oral Hydrocortisone Granules with Taste Masking for the Treatment of Neonates and Infants with Adrenal Insufficiency

29. March 2016

29. March 2016 Background: Current treatment for adrenal insufficiency in neonates and infants is unsatisfactory as unlicensed adult formulations are used...

Wet Granulation Knowledge Brief

28. March 2016

28. March 2016 Granulation is the process of joining multiple particles or grains together, typically using a binding agent although...

Comparison of metoprolol tartrate multiple-unit lipid matrix systems produced by different technologies

18. March 2016

The aim of this study was to develop, evaluate and compare extended release mini-matrices based on metoprolol tartrate (MPT) and...

“Design Space” Determination of a Paracetamol Fluid Bed Granulation Using Design of Experiments

20. January 2016

20. January 2016 This study was performed to increase understanding of a paracetamol fluid bed granulation process and to identify...

Development of novel multifunction directly compressible co-processed excipient by melt granulation technique

27. October 2015

27. October 2015 Introduction: The objective of the present investigation was to develop a novel multifunctional directly compressible co-processed...

AN INVESTIGATION INTO TASTE MASKING OF A MICRONIZEDPARACETAMOL USING AQUACOAT® ECD APPLIED VIA DIFFERENTGRANULATION PROCESSES

17. September 2015

INTRODUCTION AND PURPOSE Taste masking is a very important step in the development of paediatric medications such as oral suspensions...

Effect of Reprocessing and Excipient Characteristics on Ibuprofen Tablet Properties – Article

5. August 2015

Purpose: To determine excipient and ibuprofen: excipient mixture sensitivity to reprocessing produced by either direct compression or wet granulation. ...

The Role of Different Binary Binder Systems on Ibuprofen-Tablets by Dry Granulation (Roller Compaction)

16. August 2013

P. Müsse, Hochschule Fresenius University of Applied Sciences, 65510 Idstein, Germany / Dr. M. Yunis, BIOGRUND GmbH, 65510 Huenstetten,...

Granulation