A shear cell study on oral and inhalation grade lactose powders

29. May 2020

Shear cell tests have been conducted on twenty different lactose powders, most of which commercially available for oral or inhalation...

In-line temperature measurement to improve the understanding of the wetting phase in twin-screw wet granulation and its use in process development

29. May 2020

Wetting is the initial stage of wet granulation processes during which the first contact between the powder and the liquid...

Free Whitepaper – Lactose properties in 3D powder bed printing

26. May 2020

The whitepaper shows results of tested 20 lactose grades in 3D powder bed printing. The primary objective of this study...

Metformin Hydrochloride- and Glyburide-Containing Orally Disintegrating Tablets

25. May 2020

Diabetes is characterized by chronic hyperglycemia. Although metformin hydrochloride (MHCl)- and glyburide (GLB)-containing conventional tablets are available in the market...

Quantification of tablet sensitivity to a stress concentration: Generalization of Hiestand’s approach and link with the microstructure

21. May 2020

Sensitivity to a stress concentration is important for the development of pharmaceutical tablets as it is related to defects like...

Techniques used for characterizing dried phage formulations

The Stabilizing Excipients in Dry State Therapeutic Phage Formulation

20. May 2020

Phage therapy has gained prominence due to the increasing pathogenicity of “super bugs” and the rise of their multidrug resistance...

New Orodispersible Mini Tablets of Enalapril Maleate by Direct Compression for Pediatric Patients

16. May 2020

BACKGROUND: In many countries, the hypertension in the pediatric population is considered an important risk of mortality and morbidity. In...

Spray drying of API nanosuspensions: Importance of drying temperature, type and content of matrix former and particle size for successful formulation and process development

11. May 2020

Active pharmaceutical ingredient (API) nanosuspensions from naproxen (Nap) and itraconazole (Itra) stabilized with Kollidon®VA64 (KVA) and sodium dodecyl sulfate (SDS)...

In-Situ Forming Vesicles for the Improvement of the Bioavailability of Fexofenadine HCl

7. May 2020

Drug absorption from the gastrointestinal tract (GIT) is one of the major problems affecting the bioavailability of orally absorbed drugs....

$Scheme of a RCDG, in-and on-line laser diffraction$

Development and Evaluation of an In-line and On-line Monitoring System for Granule Size Distributions in Continuous Roll Compaction/Dry Granulation Based on Laser Diffraction

1. May 2020

Roll compaction/dry granulation is established in manufacturing of solid oral dosage forms and, within the context of continuous manufacturing, it...

Lactose