Lipid nanoparticles

Abstract Hybrid lipid nanocapsules (hLNCs) represent a promising platform for mRNA delivery with the added benefit of ambient-temperature stabilization. Conventional...

Abstract Ezetimibe is a cholesterol absorption inhibitor widely used in the treatment of dyslipidemia. However, its clinical efficacy is limited...

Abstract Liver diseases—encompassing hepatitis, liver fibrosis, fatty liver, and hepatocellular carcinoma—constitute a formidable global health challenge. Existing treatments are often...

Abstract Lipid nanodispersions are a promising formulation strategy for improving the bioavailability of drugs that are poorly water-soluble but highly...

Abstract Tacrolimus (TAC), a calcineurin inhibitor used topically for T-cell-mediated skin diseases, faces challenges due to poor solubility and limited...

Abstract mRNA delivered by microneedle patch (MNP) can enable painless delivery, reduced need for healthcare expertise, and improved thermostability. In...

Abstract Oral administration is the best way to administer both traditional and novel drugs because it decreases patient non compliance...

Abstract Lyophilization enhances mRNA vaccine stability, but conventional approaches using external trehalose for lipid nanoparticle (LNP) colloidal stability neglect mRNA...

Abstract Introduction: The cold-burst method presents a novel, energy-efficient, and cost-effective approach for solid lipid nanoparticle (SLN) production compared to...

Abstract Ketoconazole (KTZ) functions by suppressing the propagation of ergosterol, an essential element of the fungal cell membrane. However, its...