Lipid Nanoparticles

Abstract Introduction Globally, lung cancer is one of the most common types of cancer. Despite advances in treatment, the clinical...

Abstract Mucopolysaccharidosis type I (MPS-I) is a rare, multisystemic lysosomal storage disease (LSD) caused by mutations in the IDUA gene, which encodes...

Why Evonik established a presence in Vancouver and Cambridge: to be close to cutting-edge science, innovative startups, and the next...

Biopharmaceutical excipients are the inactive substances added to biologic drug products to protect large, structurally fragile biomolecules, such as monoclonal...

Messenger RNA (mRNA) is intrinsically unstable due to spontaneous 2'-hydroxyl-mediated phosphodiester hydrolysis, with degradation rates accelerating at pH below 5.0...

Abstract Entacapone is a catechol-O-methyltransferase (COMT) inhibitor, widely used for the symptomatic treatment of Parkinson’s disease. However, it presents setbacks...

Abstract The taste of a drug formulation, especially of orodispersible and liquid dosage forms, is of crucial importance due to...

Abstract Purpose Conventional chemotherapy is limited by premature drug leakage, systemic toxicity, and inefficient intracellular co-delivery, leading to reduced therapeutic...

Abstract The anti-glaucoma drug betaxolol hydrochloride (BH) exhibits poor ocular bioavailability due to limited corneal permeability, rapid precorneal loss, short...

Abstract Tolcapone is a nitrocatechol-based drug used as adjuvant therapy in Parkinson’s Disease (PD). Despite being effective in managing PD-associated...