Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm

11. December 2021

Lipid nanoparticle (LNP) is commonly used to deliver mRNA vaccines. Currently, LNP optimization primarily relies on screening ionizable lipids by...

Formulation and characterization of hydroxyethyl cellulose-based gel containing metronidazole-loaded solid lipid nanoparticles for buccal mucosal drug delivery

3. December 2021

Local delivery of drug is a promising strategy to manage periodontitis characterized by chronic inflammation of the soft tissue surrounding...

Are lipid nanoparticles really superior? A holistic proof of concept study

2. December 2021

Lipid nanoparticles are a successful carrier system for dermal drug delivery. They possess various beneficial properties, i.e., increased chemical stability...

A schematic of three different classes of lipid-based nanoparticles

Lipid Nanoparticles for Drug Delivery

2. December 2021

Lipid nanoparticles have attracted significant interests in the last two decades, and have achieved tremendous clinical success since the first...

figure 1 of Chitosan hydrogel for topical delivery of ebastine loaded solid lipid nanoparticles for alleviation of allergic contact dermatitis

Chitosan hydrogel for topical delivery of ebastine loaded solid lipid nanoparticles for alleviation of allergic contact dermatitis

30. November 2021

Ebastine, is an antihistamine drug that exerts its effect upon oral administration in humans for the treatment of allergic contact...

Lipid Nanoparticles Loaded with Farnesol or Geraniol to Enhance the Susceptibility of E. coli MCR-1 to Colistin

11. November 2021

Resistance to colistin, one of the antibiotics of last resort against multidrug-resistant Gram-negative bacteria, is increasingly reported. Notably, MCR plasmids...

graphical abstract of Combination of lipid nanoparticles and iontophoresis for enhanced lopinavir skin permeation: Impact of electric current on lipid dynamics

Combination of lipid nanoparticles and iontophoresis for enhanced lopinavir skin permeation: Impact of electric current on lipid dynamics

29. October 2021

Nanostructured lipid carriers (NLC)-loaded with lopinavir (LPV) were developed for its iontophoretic transdermal delivery. Electronic paramagnetic resonance (EPR) spectroscopy of fatty acid spin...

FTIR spectra of SC, Compritol® 888 ATO, SLN-SC, and NLC-SC. The area circled highlights the difference in the absorption bands between Compritol® 888 ATO and the nanocarriers (SLN-SC and NLC-SC)

Nanostructured lipid carriers as a novel tool to deliver sclareol: physicochemical characterisation and evaluation in human cancer cell lines

7. October 2021

Sclareol (SC) is arousing great interest due to its cytostatic and cytotoxic activities in several cancer cell lines. However, its...

graphical abstract of Formulation and assessment of hydroxyzine HCL solid lipid nanoparticles by dual emulsification technique for transdermal delivery

Formulation and assessment of hydroxyzine HCL solid lipid nanoparticles by dual emulsification technique for transdermal delivery

27. September 2021

Hydroxyzine HCL (HHCL) is an antihistamine, used for the treatment of allergic skin conditions. The purpose of this study was to achieve a...

graphical abstract of Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active

Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active

7. September 2021

Lipid nanoparticles have been widely investigated for their use as either carriers for poorly water soluble actives or as (Pickering)...

Lipid Nanoparticles