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Introduction Magnesium stearate (MgSt) is a common lubricant that is added to tablet formulations to reduce the friction between granules...
Abstract Successful development of direct-compression formulations can be hindered by poor compactibility of active pharmaceutical ingredients active pharmaceutical ingredients (APIs),...
Formulation Challenges in Low-Dose Fixed-Dose Combinations Developing fixed-dose combination (FDC) therapies presents unique formulation challenges, particularly when one active pharmaceutical...
Abstract The Knowledge-Aided Assessment and Structured Application (KASA) is an initiative led by the FDA’s Center for Drug Evaluation and...
A new model was developed to predict the tensile strength of tablets compressed from a lubricated dry powder blend by...
Press Release | November 18, 2025 SHANGHAI, China, Nov. 18, 2025 — DuPont (NYSE: DD) today held a groundbreaking ceremony for...
Inertness Compritol® 888 ATO is inert Compritol® 888 ATO - glyceryl dibehenate - does not react with active pharmaceutical ingredients...
Abstract The development of robust oral tablet formulations remains time-consuming, often limited by scarce data and the difficulty of incorporating...
Abstract Background: Polyols are widely used as tablet diluents due to their high solubility, favourable taste, and ability to form...
Abstract The pharmaceutical industry is increasingly adopting co-processed excipients as alternatives to conventional excipients in tablet manufacturing despite certain regulatory...
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