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Background: Theacrine (1,3,7,9-tetramethyluric acid, TC) is a purine alkaloid rich in the tender leaves of an unusual Chinese tea known...
As commonly known, the product development stage is quite complex, requires intensive knowledge, and is time-consuming. The selection of the...
Lubricants are indispensable pharmaceutical ingredients for preventing tableting failure due to powder adhesion to the die wall. The impact of...
The delivery of antihistaminic agents via the oral route is problematic, especially for elderly patients. This study aimed to develop...
The design and manufacture of tablets is a challenging process due to the complex interrelationships between raw material properties, the...
Minitablets are an appealing option for an age-appropriate pediatric dosage form. In particular, for combination therapies where multiple active ingredients...
“Continuous Manufacturing (CM)” is a manufacturing method in which raw or blended materials are continuously charged to the processing line,...
The U.S. Food and Drug Administration (FDA) emphasizes drug product development by Quality by Design (QbD). Critical material attributes (CMAs)...
There is a high unmet medical need for child-appropriate oral dosage forms. The acceptability of a novel placebo orally dispersible...
The suitability of pharmaceutical binders for continuous twin-screw wet granulation was investigated as the pharmaceutical industry is undergoing a switch...
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