Lubricant

Punch sticking during tablet manufacturing is a common problem facing the pharmaceutical industry. Using several model compounds, effects of crystal...

At moderate stresses, shear cells are the preferred method of powder flow measurement. However, several industrial processes operate at low...

This study aimed to transfer a high shear granulation (HSG) process to a twin-screw granulation (TSG) process while maintaining equivalent...

In tablet manufacturing, a lubricant is added in a tumbling mixer prior to compression to ensure that the tablet is...

Polymer-based long-acting matrix tablets are often used to ensure patient compli- ance and API efficacy of orally applied drugs. Increasingly,...

Lubricants are important for both preserving the tooling of high-speed tablet presses and attaining quality tablets. Magnesium stearate (MgSt) is...

Roller compaction is the main technique employed in dry granulation. Ribbon sticking and splitting are among the major factors that...

A design of experiments (DOE) approach (2-level full factorial design) was used to investigate the effect of several formulation and...

Continuous manufacturing (CM) is a promising strategy to achieve various benefits in the context of quality, flexibility, safety and cost...

Tablet quality can be affected by material, configuration and design of the tooling which comprise punches and dies. Much research...