Mannitol

Abstract Background/Objectives: The aim of this study was to develop and apply a novel integrated approach for predicting local mucosal tolerability...

Abstract Spray freeze-drying (SFD) is a cutting-edge technique for producing dry powders, ideal for pulmonary drug delivery, owing to its...

Abstract The generation of N-nitrosamine compounds (NOCs) in drugs presents a critical regulatory challenge owing to their potential mutagenicity and exceptionally...

Abstract The stability of moisture-sensitive active pharmaceutical ingredients (APIs) in solid dosage forms is a key determinant of product quality...

Abstract Capsule aperture geometry is a tunable design parameter that can markedly influence powder emission and aerosol dispersion in capsule-based...

FROM CHALLENGE TO TRIUMPH Effervescent tablets pose unique formulation challenges — balancing tablet strength, dissolution, and appearance while managing large...

Abstract Air entrapment is a primary cause of tablet lamination, yet the quantitative impact of specific tooling variables remains underexplored....

Abstract The dynamic and transitory nature of the distal small intestine makes targeted drug delivery to this region particularly challenging....

Abstract Therapeutic proteins have emerged as a cornerstone of modern medicine due to their high specificity and strong biological effects....

Abstract Dissolution testing is performed to understand the rate and extent of drug release for assurance of in vivo bioavailability. In this...