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Abstract mRNA delivered by microneedle patch (MNP) can enable painless delivery, reduced need for healthcare expertise, and improved thermostability. In...
Abstract The transdermal delivery of large molecules such as proteins and vaccines faces enormous challenges and at the same time...
Abstract Peptide therapeutics are important in healthcare owing to their high target specificity, therapeutic efficacy, and relatively low side effect...
Abstract Olanzapine (OLZ) is classified as a typical antipsychotic drug utilized for treatment of schizophrenia, it possesses poor oral bioavailability...
Abstract Vaginal drug delivery has gained significant interest due to its numerous advantages, such as good blood flow, bypassing the...
Abstract SmartReservoirs (SRs) are novel drug reservoirs made from a cellulose-based matrix for hydrogel-forming microneedles (HF-MNs). SRs can incorporate drug...
Abstract Hydrogel-forming microarray patches (MAPs) offer a minimally invasive platform for transdermal drug delivery, enabling systemic absorption of active pharmaceutical...
Abstract The safety of repeated microarray patch (MAP) application is crucial for its development as an innovative drug delivery platform....
Abstract In commercial applications, sofosbuvir (SOF) for hepatitis C is only available in tablet dosage form, resulting in minimal SOF...
Abstract To address incomplete drug release in monolithic dissolving microneedle (DMN) patches caused by non-selective drug dispersion into the backing...
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