Monoclonal Antibodies

Abstract Preservatives are critical for preventing microbial contamination in multi-dose biologics, yet their compatibility with proteins poses a major challenge....

Abstract Background/Objectives: The development of dry powder formulations for pulmonary delivery of therapeutic antibodies requires careful stabilization strategies to preserve...

Abstract Host cell proteins (HCPs) are process-related impurities in a therapeutic protein expressed using cell culture technology. This review presents...

Abstract Permeation enhancers (PE) such as hyaluronidase are increasingly incorporated into subcutaneous (SC) biologic drug formulations to improve drug absorption....

Abstract Background: Despite the growing importance of polypeptide-based drugs in clinical therapy, studies investigating the stability of their freeze-dried formulations...

Abstract High dose biologic drug products (DPs) have become a common trend for the treatment of chronic diseases across a...

Press Release Waukegan, IL – Pfanstiehl, a global leader in high-purity excipient manufacturing, announces the release of its High Purity Low...

Abstract Despite remarkable advances in cancer therapeutics, conventional treatments still face significant hurdles, including systemic toxicity, poor tumor specificity, multidrug...

Abstract Protein-based drugs are prone to both physical and chemical instability in aqueous solutions. Surfactants, such as polysorbates (PS), are...

Abstract Peptide therapeutics are important in healthcare owing to their high target specificity, therapeutic efficacy, and relatively low side effect...