Are you facing the challenge to replace titanium dioxide (TiO2) in your coating formulations?

 

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For decades, TiO2 is used as a white pigment due toits very high opacity and brightness. Therefore, it has a wide range of applications, from colouring ingredient of pharmaceutical film coating, to food application colouring.

 

On the basis of current discussions on a new classification and labelling of TiO2 and EFSA’s re-evaluation of TiO2 (E171) as a food additive, BIOGRUND is committed to offer alternatives for common film coating formulations. To address this issue, BIOGRUND developed alternatives to replace titanium dioxide in existing film coating systems.

 

AquaPolish®, formulated without TiO2, provides a comparable white film coating for oral solid dosage forms. Differences to the use of titanium dioxide are not apparent to the eye. The opacity is similar even when used on dark tablet cores.

AquaPolish® containing TiO2
AquaPolish® containing TiO2
uncoated tablet core
uncoated tablet core
AquaPolish® without TiO2
AquaPolish® without TiO2

 

If required, coloured film coating systems can be replaced TiO2 free. According to customer requirements light-stable natural pigments can be used in the formulation when synthetic colours and iron oxides are not allowed.

The top row shows the tablets, which are coated in natural colors. The lower row shows their stability to light after a solar radiation of 24 hours.

 

We support you in the reformulation of your existing formula or new project developments.

 

Get in contact with us and order a sample – free of charge!

 

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