Long-Acting Injectable Aqueous Suspensions—Summary From an AAPS Workshop

Through many years of clinical application of long-acting injectables, there is clear proof that this type of formulation does not just provide the patient with convenience, but more importantly a more effective treatment of the medication provided. The formulation approach therefore contains huge untapped potential to improve the quality of life of many patients with a variety of different diseases.

This review provides a summary of some of the central talks provided at the workshop with focus on aqueous suspensions and their use as a long-acting injectable. Elements as formulation, manufacturing, in vitro dissolution methods, in vitro and in vivo correlation, in silico modelling provide an insight into some of the current understandings, learnings, and not least gaps in the field.

Holm, R., Lee, R.W., Glassco, J. et al. Long-Acting Injectable Aqueous Suspensions—Summary From an AAPS Workshop. AAPS J 25, 49 (2023). https://doi.org/10.1208/s12248-023-00811-8

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