SEPITRAP™ offers new possibilities for formulation and improving the bioavailability of active ingredients with low solubility
Description
SEPITRAP™ is a micro-encapsulated solubilizer in powder form designed to simplify the manufacturing of solid oral form drugs. It is manufactured by adsorption of the solubilizer in liquid form on a porous support.
SEPITRAP™ is both a solid solubilizer and a compression agent. It is a functional excipient designed specifically to simplify manufacturing of dry-form drugs while improving bioavailability of the active ingredient.
There are two solubilizers in the SEPITRAP™ range:
Sepitrap™ 80 and Sepitrap™ 4000
All the components of SEPITRAP™ comply with USP-NF. SEPITRAP™ is manufactured in accordance with IPEC GMP standards and is certified EXCiPACT.
The regulatory and quality package is available on request.
Video: SEPITRAP™ & HME
Seppic offers Versatile excipient for oral solid dosage form designed for the manufacturing of tablets and capsules.
Process and bioavailability benefits
Designed for solid forms such as tablets and capsules, SEPITRAP™ can be used in direct compression procedures without impacting the hardness and disintegration of the formed tablets.
There are two kinds of benefits: bioavailability enhancement and manufacturing process optimization:
- SEPITRAP™ is designed using a patented technology
- It is a free-flowing powder
- It is suited to direct compression processes, there is no intermediary wet granulation required
- It can be used to improve the solubility of active ingredients with low water solubility
Applications
SEPITRAP is manufactured using a patented technology
SEPITRAP™ can be used to formulate tablets by direct compression but can also be used in the formulation of hard capsules.
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Following both excipients are mentioned in the study: Sepitrap™ 80 and Sepitrap™ 4000
Source: Seppic, website SEPITRAP™ | SEPPIC