Exploration of Neusilin® US2 as an Acceptable Filler in HPMC Matrix Systems—Comparison of Pharmacopoeial and Dynamic Biorelev

Exploration of Neusilin® US2 as an Acceptable Filler in HPMC Matrix Systems—Comparison of Pharmacopoeial and Dynamic Biorelevant Dissolution Study

7. January 2022

Modern pharmaceutical technology still seeks new excipients and investigates the further use in already known ones. An example is magnesium...

Application of a novel electrostatic dry powder coating technology on capsules for enteric release

6. January 2022

Dry coating of pharmaceutical dosages represents the future of functional coating given its environmental friendliness and cost effectiveness. Based on...

Extrudates:agglomerates obtained after extrusion of metformin HCl

Comparison of Hydroxypropylcellulose and Hot-Melt Extrudable Hypromellose in Twin-Screw Melt Granulation of Metformin Hydrochloride: Effect of Rheological Properties of Polymer on Melt Granulation and Granule Properties

3. January 2022

High-molecular-weight hypromellose (HPMC) and hydroxypropyl cellulose (HPC) are widely known, extended-release polymers. Conventional high-molecular-weight HPMCs are preferred in extended-release applications...

3D-Printed Coating of Extended-Release Matrix Tablets Effective Tool for Prevention of Alcohol-Induced Dose Dumping Effect

14. December 2021

Tablets used for extended drug release commonly contain large amounts of drugs. The corresponding drug release mechanism thus has to...

graphical abstract of Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design

Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design

7. December 2021

In this study, we developed a control strategy for a drug product prepared by high-shear wet granulation and roller compaction...

The Effect of Capsule-in-Capsule Combinations on In Vivo Disintegration in Human Volunteers: A Combined Imaging and Salivary Tracer Study

1. December 2021

Controlling the time point and site of the release of active ingredients within the gastrointestinal tract after administration of oral...

graphical abstract of Understanding the Effect of Energy Density and Formulation Factors on the Printability and Characteristics of SLS Irbesartan Tablets - Application of the Decision Tree Model

Understanding the Effect of Energy Density and Formulation Factors on the Printability and Characteristics of SLS Irbesartan Tablets—Application of the Decision Tree Model

27. November 2021

Selective laser sintering (SLS) is a rapid prototyping technique for the production of three-dimensional objects through selectively sintering powder-based layer...

PXRD patterns for (A) At-HPC mixture, (B) At-CMC mixture, (C) At-MCC mixture, (D) At-PGS mixture, and (E) At-SSG mixture at temperature of (a) 25 °C, (b) 65 °C, (c) 85 °C, (d) 105 °C, (e) 125 °C, (f) 135 °C, (g) 145 °C, (h) 155 °C, and (i) after cooling to 25 °C

Quantification of Compatibility Between Polymeric Excipients and Atenolol Using Principal Component Analysis and Hierarchical Cluster Analysis

26. November 2021

An important challenge to overcome in the solid dosage forms technology is the selection of the most biopharmaceutically efficient polymeric...

graphical abstract of Clinical Demonstrations of Controlled-Release Tablets Constructed by the Combined Usage of Shellac and Hydroxypropyl Methylcellulose

Clinical Demonstrations of Controlled-Release Tablets Constructed by the Combined Usage of Shellac and Hydroxypropyl Methylcellulose

25. November 2021

A new tablet system was examined for an intestinal delivery system using hydroxypropyl methylcellulose (HPMC) and shellac. HPMC was incorporated...

graphical abstract of Cyclodextrin as Functional Carrier in Development of Mucoadhesive Tablets Containing Polygoni cuspidati Extract with Potential for Dental Applications

Cyclodextrin as Functional Carrier in Development of Mucoadhesive Tablets Containing Polygoni cuspidati Extract with Potential for Dental Applications

25. November 2021

Polygoni cuspidati root is a resveratrol-rich source with anti-inflammatory, angiogenic and neuroprotective effects. The raw material was standardized for the content...

HPMC - Hydroxypropylmethylcellulose

Exploration of Neusilin® US2 as an Acceptable Filler in HPMC Matrix Systems—Comparison of Pharmacopoeial and Dynamic Biorelevant Dissolution Study

Application of a novel electrostatic dry powder coating technology on capsules for enteric release

Comparison of Hydroxypropylcellulose and Hot-Melt Extrudable Hypromellose in Twin-Screw Melt Granulation of Metformin Hydrochloride: Effect of Rheological Properties of Polymer on Melt Granulation and Granule Properties

3D-Printed Coating of Extended-Release Matrix Tablets Effective Tool for Prevention of Alcohol-Induced Dose Dumping Effect

Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design

The Effect of Capsule-in-Capsule Combinations on In Vivo Disintegration in Human Volunteers: A Combined Imaging and Salivary Tracer Study

Understanding the Effect of Energy Density and Formulation Factors on the Printability and Characteristics of SLS Irbesartan Tablets—Application of the Decision Tree Model

Quantification of Compatibility Between Polymeric Excipients and Atenolol Using Principal Component Analysis and Hierarchical Cluster Analysis

Clinical Demonstrations of Controlled-Release Tablets Constructed by the Combined Usage of Shellac and Hydroxypropyl Methylcellulose

Cyclodextrin as Functional Carrier in Development of Mucoadhesive Tablets Containing Polygoni cuspidati Extract with Potential for Dental Applications

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