Microcrystalline Cellulose

Abstract Sticking can significantly affect drug product quality, manufacturing efficiency, and therapeutic efficacy in pharmaceutical tablet manufacturing. This study presents...

Abstract The pharmaceutical drug product development process can be greatly accelerated through the use of modeling and simulation techniques to...

Abstract We study the response of two twin-screw granulators of different barrel diameter to the variation of three process parameters...

Abstract Orodispersible films (ODFs), easy to administer, flexible in dosage, and free of choking and aspiration risks, have drawn widespread...

Abstract The porosity of a pharmaceutical tablet influences liquid transport, disintegration and dissolution, rendering its monitoring and control crucial for...

Abstract Chlorothiazide (CTZ), a widely used thiazide diuretic, exhibits poor and variable oral bioavailability due to site-specific absorption and carrier-mediated...

Introduction There are several approaches in order to develop tablet formulations. On the one hand, high functionality excipients that follow...

Abstract It is widely believed that compaction simulators can replicate the uniaxial compression process of a roller compactor. The correction...

Abstract The provision of effective probiotic formulations requires gentle processing to maintain the viability of the probiotic microorganisms, which is...

Abstract Roller compaction/dry granulation (RC/DG) is a key process in pharmaceutical manufacturing for improving powder flowability, density, and segregation resistance....