Microcrystalline Cellulose

TopMill, a milled ready-to-use pigment and dye premix, produced tablet cores with no by-eye detectable defects in direct compression trials,...

Abstract The generation of N-nitrosamine compounds (NOCs) in drugs presents a critical regulatory challenge owing to their potential mutagenicity and exceptionally...

Abstract Punch sticking is a well-recognized and extensively studied challenge in pharmaceutical tablet manufacturing. However, the impact of solid-form impurities...

Abstract Press-coated tablets (PCTs) are a modern dosage form designed to circumvent the negative effects of liquid and heat exposure...

Abstract Alfuzosin hydrochloride, an α1-adrenergic antagonist used in the treatment of benign prostatic hyperplasia (BPH), was formulated as orodispersible tablets...

Influence of Water on the Structure of MCC Influence of Water on the Structure of MCC describes how moisture reshapes...

Abstract The stability of moisture-sensitive active pharmaceutical ingredients (APIs) in solid dosage forms is a key determinant of product quality...

Abstract We developed a headspace gas chromatography method with flame ionization detection (HSGC-FID) for trace nitrite determination in pharmaceutical excipients....

Introduction Soft tabletting of pellets is a specialized pharmaceutical compaction technology preserving coated pellet integrity during tablet compression. It combines...

Pharmaceutical tableting continues to be a vital step in manufacturing oral solid dosage forms. Even with progress in formulation science...