Organic Chemicals

Abstract Objectives: A customizable 3D-bioprinted core-in-shell platform was developed for time-dependent oral colon delivery of live microorganisms. The system conveyed Lacticaseibacillus paracasei as...

Capsugel® Enprotect® capsule enables enteric delivery without the need for a post-filling coating step. This helps protect your sensitive active...

Abstract Despite their widely recognized performance-related benefits, nanosuspensions (NSs) present major challenges, mainly due to their poor stability during storage....

Abstract Amorphous solid dispersions (ASDs) are widely used to enhance the solubility of poorly water-soluble drugs. Among commercial manufacturing approaches,...

Abstract High drug-loaded immediate-release formulations can be produced using a solvent-free and continuous melt-granulation method with a twin-screw extruder. Known...

Abstract Novel bitter-taste-masking microparticles for loading in orally disintegrating (OD) tablets have been developed using a mechanical powder processor. Swellable...

Abstract Biomacromolecules including peptides, proteins, antibodies, and gene medicines, comprise important classes of therapeutics in treating disease. A drawback of...

Abstract Background/Objectives: The objective of this study was to design and optimize a continuous wet granulation process for Amiodarone hydrochloride...

Abstract This research evaluated the viability of powder discharge-based KinetiSol (pKSD) as a rapid, solvent-free particle engineering technology for producing...

Abstract Background: Hot-melt extrusion (HME) is a promising technology for the manufacturing of drug products; however, its application is limited by...