Trehalose

Enzymes are essential biocatalysts and very attractive as therapeutics. However, their functionality is strictly related to their stability, which is...

Proteins and peptides have become an important class of therapeutics due to their high specificity and general biocompatibility. However, using...

Nanoparticles have shown considerable potential in many biological applications including drug delivery, bio-imaging, and medical diagnostics. Specifically, the development of...

The oral bioavailability of therapeutic proteins is limited by the gastrointestinal barriers. Encapsulation of labile proteins into nanoparticles is a...

Pfanstiehl (IL, USA) is a global leader in developing High Pure/Low Endotoxin Viral Vector, Protein and Vaccine stabilizers ( eg....

The properties of trehalose + water mixtures are studied as a function of mixture composition and temperature using molecular dynamics...

We have observed an interesting phenomenon in which grinding of freeze-dried monoclonal antibody X (mAb-X) formulation powder resulted to significant...

Freeze-drying, until now, has been a process that was designed using a trial and error experimental approach. This approach is...

Drying of coacervates can cause various stresses which may lead to the damage of the outer layer membrane, aggregation, and...

Intracellular/extracellular protein aggregation is linked to variety of neurodegenerative diseases. Current research focusses on identifying anti-amyloidogenic small molecules to inhibit...