Trehalose

Ketoconazole (K) is a poorly water-soluble drug that faces significant challenges in achieving therapeutic efficacy. This study aimed to enhance...

Abstract As of 2023, more than 200 million people worldwide are living with osteoporosis. Oral bisphosphonates (BPs) are the primary...

The manufacturing of tablets containing biologics exposes the biologics to thermal and shear stresses, which are likely induce structural changes...

Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) continue as public health concerns. Inhaled drug therapy for TB has substantial...

Extracellular vesicles (EVs) have emerged as a promising drug delivery system. Connectosomes are a specialized type of EVs that contain...

Abstract Biopharmaceuticals are labile biomolecules that must be safeguarded to ensure the safety, quality, and efficacy of the product. Batch...

Abstract Among the various pharmaceutical forms, tablets offer numerous advantages, like ease of administration, cost-effectiveness in production, and better stability...

SOLBIOTE (TM) – Injectable-grade Saccharide Excipients for Biopharmaceuticals Nagase Viita, the first company in the world to mass produce Trehalose, has...

Abstract Sugars have long been used as stabilizing excipients for protein-based therapeutics during the development and production process. Incorporating stabilizing...

The present study compared vacuum drum drying (VDD) and conventional spray drying (SD) for solidifying crystalline ABT-199 nanosuspensions into redispersible...