Trehalose

Abstract Posaconazole (PCZ) is a broad spectrum anti-fungal drug approved by FDA and currently used off-label for the treatment of...

The transition of immunotherapy administration from intravenous infusion to subcutaneous (SC) administration of monoclonal antibody formulations for oncology patients has...

Abstract Similar to other routes of administration, pulmonary formulations typically contain excipients. The panel of substances that can be used...

Abstract This research study aimed to develop and evaluate a novel freeze-dried nanocrystals formulation of sotorasib (AMG-510) using Quality by...

Abstract Vaccines rely on a global cold chain to maintain vaccine potency throughout the product life cycle. Existing vaccine thermostabilization...

Abstract The provision of effective probiotic formulations requires gentle processing to maintain the viability of the probiotic microorganisms, which is...

Abstract For monoclonal antibody drug products as for other biologics, while the innovator drug products first becomes commercially available, they...

Abstract Lipid nanoparticles (LNPs) have demonstrated their therapeutic potential as safe and effective drug delivery systems for nucleic acids during...

Abstract Background: Dry powders offer the potential to increase stability and reduce cold-chain requirements associated with the distribution of vaccines and...

The FDA approved 50 novel drugs in 2024, marking another milestone year in pharmaceutical innovation. While various summaries have highlighted...