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Paediatric
Colour of Medicines and Children’s Acceptability? A Systematic Literature Review of Children’s…
The colour of a product plays an important role in consumer experiences, and in the context of pharmaceutical products, this could potentially affect a patient’s expectations, behaviours, and adherence. Several studies have been conducted on adults, but little is known about children’s opinions on…
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Putting children first: Understanding caregivers’ and children’s perspectives on the usability of…
A multi-national online survey was developed to obtain feedback on users’ experiences of administration devices for oral and inhaled paediatric medicines. The questionnaire was divided into two identical parts: 1) for caregivers looking after children aged 0–18 years, and 2) for children aged 10 …
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3D Printed Flavor-Rich Chewable Pediatric Tablets Fabricated Using Microextrusion for Point of Care…
Abstract
Over the past few years, 3D printing technologies have gained interest in the development of medicinal products for personalized use at the point of care. The printing of drug products offers personalization and flexibility in dose, shape/design, and flavor, potentially enhancing…
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Development of Child-Friendly Lisdexamfetamine Chewable Tablets Using Ion Exchange Resin as a…
Taste masking is critical to improving the compliance of pediatric oral dosage forms. However, it is challenging for extremely bitter lisdexamfetamine dimesylate (LDX) with a long half-life and given in large dose. The present study aims to develop an immediate-release, taste-masked lisdexamfetamine…
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Revolutionizing pediatric HIV therapy: The latest breakthroughs in drug delivery techniques
Human Immunodeficiency Virus (HIV) is the root cause of acquired immunodeficiency syndrome (AIDS), which destroys the body's immune cells, thereby rendering the body unable to fight any infections. It is a sexually transmitted disease (STD) in adults but in children, it is passed on from an…
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Gin & tonic – the first bittersweet antimalarial
During the 1700s, antimalarial properties of quinine were first unleashed. British soldiers stationed in India began drinking tonic water to prevent and combat the disease. However, quinine has a pronounced bitter taste; in the 1800s, gin was added to make the tonic more palatable. Later, lemon and…
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Preliminary Study on the Development of Caffeine Oral Solid Form 3D Printed by Semi-Solid Extrusion…
Apnea of prematurity can be treated with a body-weight-adjusted dosage of caffeine. Semi-solid extrusion (SSE) 3D printing represents an interesting approach to finely tailor personalized doses of active ingredients. To improve compliance and ensure the right dose in infants, drug delivery systems…
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Development of a New Age-Appropriate, Chewable Tablet of Mebendazole 500 mg for Preventive…
The aim of this study was to develop an age-appropriate tablet of mebendazole 500 mg to be used in large donation programs by the World Health Organization (WHO) for preventive chemotherapy of soil-transmitted helminth (STH) infections in pre-school and school-age children living in tropical and…
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Design, Evaluation and Comparison of Nanostructured Lipid Carriers and Chitosan Nanoparticles as…
There is a serious need of pediatric drug formulations, whose lack causes the frequent use of extemporaneous preparations obtained from adult dosage forms, with consequent safety and quality risks. Oral solutions are the best choice for pediatric patients, due to administration ease and…
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Stability of Oral Liquid Dosage Forms in Pediatric Cardiology: A Prerequisite for Patient’s Safety—A…
The development of safe and effective pediatric formulations is essential, especially in therapeutic areas such as pediatric cardiology, where the treatment requires multiple dosing or outpatient care. Although liquid oral dosage forms are considered the formulation of choice given the dose…
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