Pharma Excipients

Parenteral Excipients

Vitamin E TPGS by PMC Isochem

D-tocopheryl polyethylene glycol succinate (Vitamin E TPGS) has been approved as a safe pharmaceutical adjuvant by FDA, and several drug delivery systems (DDS) based on TPGS have been developed. TPGS hase interesting properties as a P-gp inhibitor, solubilizer/absorption and permeation enhancer in…
Read More...

Biodegradable polymers for parenteral drug delivery

Functional lactide/glycolide polymers play a key role in complex parenteral drug delivery products. They are often referred to as ‘smart’ materials, as their tunability drives the performance of parenteral dosage forms. Using these polymers, formulators can deliberately change drug impact by…
Read More...

Long acting injectables for therapeutic proteins

Biotherapeutic development presents a myriad of challenges in relation to delivery, in particular for protein therapeutics. Protein delivery is complicated due to hydrophilicity, size, rate of degradation in vivo, low permeation through biological barriers, pH and temperature sensitivity, as well as…
Read More...