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For polymer-based controlled release drug products (e.g. microspheres and implants), active pharmaceutical ingredient distribution and microporosity inside the polymer matrix...
Gelucire 48/16 is a non-ionic surfactant recommended for use in Lipid-Based Formulations (LBFs) to increase aqueous solubility and oral bioavailability...
The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. In...
The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug...
Multiparticulates such as micropellets, pellets, granules and mini-tablets represent modern and innovative technology platforms. Multiparticulates can provide a number of...
Drug layering on starter pellets is a standard technology to achieve multiparticulate dosage forms. The most widely used are still...
Dissolution media based on bicarbonate buffers closely mimic the environment of intestinal fluids and thus improve in vitro in vivo...
Compaction of multiple-unit pellet system (MUPS) tablets has been extensively reported to be potentially challenging. Thus, there is a need...
This paper presents the output of a workshop held at the 11th Annual Conference of EuPFI (European Paediatric Formulation Initiative),...
The objective of the present study was to develop a pH-sensitive drug delivery system by using polymethylmethacrylate-grafted gellan gum (PMMA-g-GG)....
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