Effect of Different Meltable Binders on the Disintegration and Dissolution Behavior of Zolmitriptan Oromucosal Fast Melt Tablets

22. February 2017

22. February 2017 Abstract Objective: Fast melt tablets and sublingual route have been widely used for providing quick onset of...

Engineering hot-melt extruded solid dispersion for controlled release of hydrophilic drugs

14. January 2017

Abstract It is often challenging to precisely manipulate the release behavior of hydrophilic drugs that is believed to be crucial...

Physical characterization and kinetic modelling of matrix tablets of ketorolac tromethamol formulated with polymers and waxes

27. December 2016

27. December 2016 Abstract Purpose: To design controlled release ketorolac tromethamol (KT) matrix tablets for increased drug bioavailability. Methods: Waxes...

Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule

15. December 2016

15. December 2016 Abstract Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft...

Effect of moisture sorption on the performance of crospovidone

22. November 2016

22. November 2016 Abstract Crospovidone is a commonly used tablet disintegrant. However, the synthetic disintegrant has been known to be...

Physical appearance of Affinisol and Plasdone S-630 extrudates

S630 polymers during Hot-melt extrusion (for 3D printing by fused deposition modelling)

22. November 2016

22. November 2016 Investigation of the processing window for Affinisol and Plasdone - S630 polymers during Hot-melt extrusion (for 3D...

How Deformation Behavior Controls Product Performance After Twin Screw Granulation With High Drug Loads and Crospovidone as Disintegrant

8. November 2016

08. November 2016 Abstract This study addresses the quantitative influence of 12 different materials (active pharmaceutical ingredients and excipients as...

Petrochemicals