Poloxamer modified florfenicol instant microparticles for improved oral bioavailability

30. April 2020

Surfactants can improve the hydrophobicity of poorly water-soluble drugs and increase the stability of microparticles by reducing surface tension. This...

Thermodynamic Aspects of the Preparation of Amorphous Solid Dispersions of Naringenin with Enhanced Dissolution Rate

28. April 2020

Amorphous ternary solid dispersions of poorly water-soluble Naringenin (NRG) in Poloxamer 188 (POX) and Neusilin US2 (NSL) were prepared in...

Kolliphor® P 188 Bio – High purity poloxamer in biologics manufacturing

17. April 2020

Manufacture of biologics in suspension cell culture causes damage to the cell membranes (shear stress). The majority of the damage...

Evolution of the microstructure and the drug release upon annealing the drug loaded lipid-surfactant microspheres

10. March 2020

The present study investigates the drug release-governing microstructural properties of melt spray congealed microspheres encapsulating the drug crystals in the...

Solid formulation of a supersaturable self-microemulsifying drug delivery system for valsartan

11. December 2017

11. December 2017 Abstract In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required...

Formulation and evaluation of nasal in situ gel of phenylephrine hydrochloride

24. March 2017

24. March 2017 Abstract In situ gel drug delivery systems are in solution form before administration but once administered, undergo...

Formulation and Evaluation of Mucoadhesive Thermosensitive in situ Gel of Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis Against HIV

24. December 2015

24. December 2015 Pre-exposure prophylaxis (PrEP) is one of the best preventive strategies in protection against HIV/AIDS. The present research...

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