AQUACOAT ECD 30

Description

This excipient is a 30 percent by weight aqueous dispersion of ethylcellulose polymer. It is a water based, pseudo latex system free of ammonia and used for solvent-free coating.
FMC has introduced Aquacoat ECS, a novel coating concept with Aquacoat.

Aquacoat® ECD is an aqueous colloidal dispersion of ethyl cellulose polymer. It is a hydrophobic material that can be used in moisture barrier and taste masking applications, and it has been used as a coating material for oral sustained release dosage forms since 19851. An aqueous dispersion of ethyl cellulose offers various processing advantages over organic ethyl cellulose solution, including reduced coating processing times, fewer environmental concerns, and the avoidance of potential toxicity related to residual solvent. In sustained release applications, Aquacoat® ECD offers a stable, reproducible, pH-independent release profile with similar dissolution profiles in the presence of fed and fasted gastric and intestinal media2. Its primary release mechanism is drug diffusion across a water-insoluble membrane.